Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron (Fe) in biological fluids. Human transferrin is encoded by the TF gene. Transferrins can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Li, Q., Yang, Q., Guo, P., Feng, Y., Wang, S., Guo, J., Tang, Z., Yu, W., & Liao, J. (2023). Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells. Food and Chemical Toxicology, published on July 21, 2023.
