top of page
YH81021S PCNA Rabbit pAb

Reactivity:

Human,Monkey,Mouse,Chinese hamster,Rat

 

Application:

WB

 

Recommended Dilution:

WB 1: 5000-20000

 

Mol Weight:

29 kDa

 

Immunogen:

PCNA polyclonal antibody is produced by immunizing rabbit with a synthetic peptide corresponding to the internal residues of human PCNA.

 

Source:

Rabbit

 

Specificity:

PCNA antibody detects endogenous levels of total PCNA protein.

YH81021S PCNA Rabbit pAb

  • PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

  • 20μl

bottom of page