Reactivity:
Human, Monkey,Bacillussubtilis
Application:
WB
Recommended Dilution:
Western blotting 1:1000
Mol Weight:
37 kDa
Immunogen:
This YH polyclonal antibody is produced by immunizing animals with a synthetic peptide (KLH-coupled) corresponding to carboxy-terminal residues of human GAPDH.
Source:
Rabbit
Specificity:
GAPDH Antibody detects endogenous levels of total GAPDH protein.
YH81014S GAPDH Rabbit pAb
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. Though differentially expressed from tissue to tissue, GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH mRNA and protein levels are often measured as controls in experiments quantifying specific changes in expression of other targets. Recent work has elucidated roles for GAPDH in apoptosis, gene expression and nuclear transport. GAPDH may also play a role in neurodegenerative pathologies such as Huntington and Alzheimer's diseases.