YH81011S GAPDH (3F10) mAb

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. Though differentially expressed from tissue to tissue, GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH mRNA and protein levels are often measured as controls in experiments quantifying specific changes in expression of other targets. Recent work has elucidated roles for GAPDH in apoptosis, gene expression and nuclear transport. GAPDH may also play a role in neurodegenerative pathologies such as Huntington and Alzheimer's diseases.

20μl

1. Ding, J., Cheng, X., Zeng, C., Zhao, Q., Xing, C., Zhang, C., Cao, H., Guo, X., Hu, G., & Zhuang, Y. (2024). Aflatoxin B1 promotes pyroptosis in IPEC-J2 cells by disrupting mitochondrial dynamics through the AMPK/NLRP3 pathway. Journal of Agricultural and Food Chemistry, published on December 4, 2024.
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