Reactivity：
Human,Mouse,Rat
Application：
WB,IF
Recommended Dilution：
Western blotting1:5000 Immunofluorescence1:500
Immunogen：
This YH monoclonal antibody is produced by immunizing animals with a synthetic peptide (KLH-coupled) corresponding to the carboxy terminus of human GAPDH.
Source：
Mouse
Specificity：
GAPDH (3B3) Mouse mAbdetects endogenous levels of total GAPDH protein.
YH81009S GAPDH (3B3) mAb
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. Though differentially expressed from tissue to tissue, GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH mRNA and protein levels are often measured as controls in experiments quantifying specific changes in expression of other targets. Recent work has elucidated roles for GAPDH in apoptosis, gene expression and nuclear transport. GAPDH may also play a role in neurodegenerative pathologies such as Huntington and Alzheimer's diseases.