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sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore with emission in the far-red area of the spectrum, an analog of Cy5.5®. Like other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient, giving rise to its bright fluorescence. The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore — this minimizes non-specific binding.

The azide group of Sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst or with cycloalkynes in copper-free strain-promoted reaction.

The reagent possesses high hydrophilicity and is recommended for labeling biomolecules in an aqueous environment.

sulfo-Cyanine5.5 azide

  • Appearance: dark colored solid
    Mass spec M+ increment: 984.2
    Molecular weight: 1099.41
    CAS number: 2382994-65-0
    Molecular formula: C43H45K3N6O13S4
    Solubility: good in water, DMF, DMSO
    Quality control: NMR 1H, HPLC-MS (95%)
    Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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