Cyanine5 azide labeling reagent for Click Chemistry, available as 10 mM solution in DMSO and in solid form.
This azide is soluble in organic solvents (e.g., DMSO, DMF); therefore, the labeling reaction should be carried out with a small amount of an organic co-solvent. This azide can be used for the labeling of alkyne-modified biomolecules in mixtures of water with organic solvents. The solution in DMSO is ready for use in bioconjugation. A water-soluble sulfonated version of this reagent is also available.
Cyanine5 is an analog of Cy5®, one of the most commonly used fluorophores, which is compatible with various instruments. Cyanine5 can also be used as a replacement for DyLight® 649.
 
Lumiprobe 全新推出生命科學研究中最受歡迎的花青染料 —— Cyanine 系列。這些染料為 1970 年代廣泛應用於血管造影的經典花青染料吲哚菁綠（ICG）之改良版，具備更低的非特異性生物分子結合特性，並因其高消光係數及優異量子產率，展現出明亮且穩定的螢光表現。隨著 CMU 專利到期，這些高效能分子現已以更親民的價格，廣泛應用於各類生命科學領域。Cyanine 染料可用於標記多種目標，包括可溶性蛋白質、抗體、DNA 與寡核苷酸、胜肽（Peptides）及各類小分子。