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Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

 

Lumiprobe 全新推出生命科學研究中最受歡迎的花青染料 —— Cyanine 系列。這些染料為 1970 年代廣泛應用於血管造影的經典花青染料吲哚菁綠(ICG)之改良版,具備更低的非特異性生物分子結合特性,並因其高消光係數及優異量子產率,展現出明亮且穩定的螢光表現。隨著 CMU 專利到期,這些高效能分子現已以更親民的價格,廣泛應用於各類生命科學領域。Cyanine 染料可用於標記多種目標,包括可溶性蛋白質、抗體、DNA 與寡核苷酸、胜肽(Peptides)及各類小分子。

Cyanine5.5 maleimide

  • Appearance: dark blue powder
    Molecular weight: 850.89
    CAS number: 1593644-50-8
    Molecular formula: C46H49F6N4O3P
    IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
    Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
    Quality control: NMR 1H, HPLC-MS (95%)
    Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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