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Far red / near-infrared dye alkyne for сlick сhemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore widely used for various applications, including intact organism imaging. This reagent can be conjugated with azido groups under mild copper-catalyzed сlick сhemistry conditions.

This reagent is soluble in organic solvents, but mixtures of water with a small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules with this far red/NIR dye.

 

Lumiprobe 全新推出生命科學研究中最受歡迎的花青染料 —— Cyanine 系列。這些染料為 1970 年代廣泛應用於血管造影的經典花青染料吲哚菁綠(ICG)之改良版,具備更低的非特異性生物分子結合特性,並因其高消光係數及優異量子產率,展現出明亮且穩定的螢光表現。隨著 CMU 專利到期,這些高效能分子現已以更親民的價格,廣泛應用於各類生命科學領域。Cyanine 染料可用於標記多種目標,包括可溶性蛋白質、抗體、DNA 與寡核苷酸、胜肽(Peptides)及各類小分子。

Cyanine5.5 alkyne

  • Appearance: dark blue powder
    Molecular weight: 656.30
    CAS number: 1628790-37-3
    Molecular formula: C43H46ClN3O
    Solubility: good in organic solvents (DMF, DMSO, acetonitrile, DCM, alcohols), practically insoluble in water (5.2 uM, 3.7 mg/L)
    Quality control: NMR 1H, HPLC-MS (95%)
    Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
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