AG-27B-0005 anti-α-Tubulin, mAb (rec.) (F2C)

Produced without the use of animals. Purified from HEK 293 cell culture supernatant.

Bovine brain tubulin.

Immunocytochemistry: (1:1'000)
Western Blot: (1:1’000)

Bovine
Human
Mouse

Recognizes mouse, bovine and human α-tubulin.

Protein A-affinity purified.

本產品短期保存請置於 4°C，可穩定保存一個月，長期保存建議分裝後存於 -20°C，可穩定保存至少一年，避免反覆凍融。

1. Recombinant antibodies selected against subcellular fractions to track endogenous protein dynamics in vivo: C. Nizak, et al.; Traffic 7, 739 (2003)
2. Characterization of single chain antibody targets through yeast two hybrid: O. Vielemeyer, et al; BMC Biotechnol. 10, 59 (2010)
3. AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity: A. Di Micco, et al.; PNAS 113, e4671 (2016)
4. Pharmacological eEF2K activation promotes cell death and inhibits cancer progression: A. De Gassart, et al.; EMBO Reports 17, 1471 (2016)
5. Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity: G. Di Conza, et al.; Nat. Immunol. 22, 1403 (2021)
6. The protease DDI2 regulates NRF1 activation in response to cadmium toxicity: S.T. Ribeiro, et al.; iScience 25, 105227 (2022)
7. CDC42 regulates PYRIN inflammasome assembly: L. Spel, et al.; Cell Rep. 41, 111636 (2022)
8. NLRP3 leucine-rich repeats control induced and spontaneous inflammasome activation in cryopyrin-associated periodic syndrome: K. Theodoropoulou, et al.; J. Allergy Clin. Immunol. 151, 222 (2023)
9. HSP90beta controls NLRP3 autoactivation: L. Spel, et al.; Sci. Adv. 10, eadj6289 (2024)
10. The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation: D. Ehirchiou, et al.; Arthritis Res. Ther. 26, 119 (2024)
11. Protofilament-specific nanopatterns of tubulin post-translational modifications regulate the mechanics of ciliary beating: G. Alvarez Viar, et al.; Curr. Biol. 34, 4464 (2024)